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102 In addition, excessive alcohol in ALD damages intestinal barrier components, especially for proteins implicated in innate antibacterial defense such as 3- and 3-, increases adhesion between bacteria and the mucosal surface, causes excessive growth of intestinal bacteria, microbial product translocation 103 and ecological imbalances related to intestinal inflammation 101 and liver inflammation

Obese patients with knee osteoarthritis who were treated with semaglutide lost significantly more weight and reported substantially improved pain and function compared to patients on placebo

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References Robinson, W