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However, low- and middle-income countries (LMICs) are experiencing the steepest rise in new PD cases, largely due to demographic transition and under-recognition in the past (Masoom et al., 2018

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5 4) Tendon & connective-tissue pathways (GHR up-regulation) In tendon fibroblasts, BPC-157 up-regulates the growth-hormone receptor (GHR) at mRNA and protein levels and augments downstream JAK2 signaling in response to GHmechanisms consistent with tendon repair biology (in-vitro)