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Hypothalamic signaling mechanisms in hypertension

Overall, melatonin demonstrates a protective effect against oxidative stress by improving mitochondrial health and function in aging HGL5 cells

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Am J Physiol 265:E380E391 Howlett RA, Parolin ML, Dyck DJ, Hultman E, Jones NL, Heigenhauser GJ, Spriet LL (1998) Regulation of skeletal muscle glycogen phosphorylase and PDH at varying exercise power outputs