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Unlike traditional drugs like Phentermine or Orlistat, which either suppress appetite or block fat absorption, Semaglutide works by copying the action of a hormone called GLP-1, which controls appetite and food intake

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This randomized, double-blind, placebo-controlled trial showed that treatment with semaglutide alleviated pain related to osteoarthritis of the knee among persons with obesity and knee osteoarthritis, Bliddal and colleagues wrote