GLP-1 receptors in the mesolimbic system are implicated in the modulation of reward behavior [134], while brain imaging studies document GLP-1-induced changes in brain regions related to appetite and reward, such as the insula, amygdala, putamen, and orbitofrontal cortex [135]
ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, Collins BS, Cusi K, Das SR, Gibbons CH, Giurini JM, Hilliard ME, Isaacs D, Johnson EL, Kahan S, Khunti K, Kosiborod M, Leon J, Lyons SK, Gabbay RA (2022) Standards of care in diabetes2023
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