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It has minimal direct impact on estrogen, progesterone, cortisol, or prolactin, which is a significant advantage for women

In our study, although the glucose in the uterine fluid was still lower than that in the blood, the downregulation of GLUT4 by GLUT4-siRNA resulted in an increased glucose concentration in the uterine fluid on pregnant day 4, and this abnormal alteration rendered the uterine environment detrimental to pre-implantation embryonic development and then impaired implantation

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