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Preclinical work has suggested that glucagon receptor activation may contribute to changes in energy expenditure and substrate utilization, while GLP-1R and GIPR signaling influence intake-related and endocrine regulatory pathways

Work with a Dietitian: Consider seeing a registered dietitian nutritionist (RDN) when starting a GLP-1 RA

Morphologic alterations in the SV, a key structure for producing and maintaining the endocochlear potential (EP), decrease the EP and consequently, affect the cochlear amplification of acoustic signals leading to an increase in auditory thresholds, even in the absence of hair cell death (Gates and Mills, 2006

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