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List of GLP-1 ini6al approvals since 2005 *products no longer on the market Notable GLP-1 Agonists for Obesity The first GLP-1 drug approved for obesity was Saxenda (liraglutide) from Novo Nordisk, a twice-daily injectable that demonstrated a 7% weight reduction over a year upon its approval

Some analyses from these trials showed modest reductions in inflammatory biomarkers, including high-sensitivity C-reactive protein (hs-CRP)

Proper use and dosage instructions must be strictly followed to reduce negative effects and increase efficacy

In addition, these medications may target the appetite centers in the brain, further helping to decrease cravings and the urge to overeat