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However, their use may be limited by gastrointestinal side effects, including pancreatitis, though studies have reported safe co-administration with tacrolimus in kidney transplant recipients with post-transplant diabetes mellitus. Figure 2: Potential benefits of GLP1-RA in CKD and KTR
CYP enzymes are predominantly expressed in the liver, but are also present in the kidney, placenta, adrenal gland, gastrointestinal tract, and skin (Zhao et al
Topical prescription agents such as hydroquinone, retinoids, azelaic acid, or tranexamic acid are applied directly to affected areas and are used under medical supervision to influence pigment production and skin renewal processes