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When suggesting a mechanism for thiamines benefit to Parkinsons patients, the researchers pointed to research showing decreases of a brain enzyme related to thiamine 8 as well as research showing lower thiamine levels in the spinal fluid of Parkinsons patients 9

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Changes in body composition, energy levels, and muscle tone typically require 8-12 weeks of consistent use, though individual response varies based on dosing, lifestyle, and baseline growth hormone levels