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This approach enables incorporation of modified amino acids and other chemical modifications that may improve therapeutic properties

This pathway not only provides cells with dual defenses against lipid peroxidation but also positions FSP1 as a significant potential target for inhibiting ferroptosis

Affected people cannot cure or manage the condition at home by taking over-the-counter (OTC) vitamin B12 supplements or eating foods rich in vitamin B12

Also, glutamate excitotoxicity NMDA-mediated intra-neuronal calcium overload elevates NO synthesis contributing to oxidative stress particularly the production of reactive nitrogen species which are able to cause defects in DNA and protein phosphorylation pathway (85)