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Description

The process dissolves the freeze-dried powder into a liquid solution that can be drawn into a syringe and administered

Briefly, quantification of signal bias was performed using pharmacologically derived parameters of agonist affinity (Ka) and efficacy (tau) for each ligand in each of the three signalling pathways (cAMP accumulation, ERK1/2 phosphorylation, Intracellular Ca 2+ mobilisation)