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In addition, the GLP-1R-mediated AMPK phosphorylation pathway can also optimize the muscle fiber types, improve glycogen storage and glucose uptake, further synergistically enhancing the athletic performance of skeletal muscle [19]

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For example, in treated animals, there are notable alterations in gut microbiota composition, including increased levels of beneficial bacteria such as Lactobacillus and Prevotella, alongside reductions in bacteria linked to inflammation