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166 Additionally, numerous other loci have strong candidate genes identified, including GCKR, RREB1, SLC17A1 to SLC17A4, SLC22A12, MAF, MLXIPL, PRKAG2, HNF4G, A1CF, IGFR1, and HLF

doi:10.1016/j.jad.2011.06.005 Farokhnia M, Azarkolah A, Adinehfar F, Khodaie-Ardakani MR, Hosseini SM, Yekehtaz H, Tabrizi M, Rezaei F, Salehi B, Sadeghi SM, Moghadam M, Gharibi F, Mirshafiee O, Akhondzadeh S (2013) N -acetylcysteine as an adjunct to risperidone for treatment of negative symptoms in patients with chronic schizophrenia: a randomized, double-blind, placebo-controlled study

Most peptides degrade rapidly in the stomach and intestines, so oral preparations typically provide negligible systemic availability, generally less than 2%

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