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Anti-tumor immune cells, such as T cells, can induce tumor cells to undergo pyroptosis while simultaneously increasing ROS to trigger ferroptosis, thereby exerting anti-tumor effects (198, 199)

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Participants were randomized to receive either standard treatment with MMI alone (Control Group) or MMI plus the combined LCT/Se supplement (Intervention Group)

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Discussion Pathophysiology of CMD CMD involve interplay of a cascade of pathophysiological events ensuing in a rise in IR, accumulation of free fatty acids (FFA) in the circulation, lipid and glucose dysmetabolism, and raised levels of adipokines and cytokines [19,20,21]

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