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Sample 1, Sample 2, and Sample 3 are the 100 K concentrates obtained from size cut-off filtration, concentrates from the ion exchange chromatography, and concentrates from the size-exclusion chromatography, respectively

Obtaining definitive proof of synapses would require systematic reconstruction using serial electron microscopy on a large population of enteroendocrine cells

1 (67), and furthermore, this group found that the selective loss of alpha-cell Arx and Dnmt1 expression led to an increase in alpha-cell-derived bihormonal insulin + /glucagon + cells in mouse islets (67)