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After each sampling, an equal volume of fresh pre-equilibrated buffer was replenished to maintain system volume and sink conditions

In animal models, lithium increased intracellular glutathione levels and reduced oxygen metabolite damage, suggesting that it selectively boosts glutathione-dependent enzymes to protect against free radical stress

Epigenetic and Transcriptomic Regulation A 2021 study in Communications Biology reported that treatment with the GLP-1s exenatide reversed transcriptomic aging signatures across multiple mouse brain cell populations, including glial and neurovascular cells [7]

Severe life stress, mitochondrial dysfunction, and depressive behavior: A pathophysiological and therapeutic perspective