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Journal of Biological Chemistry 261 (25): 11880-11889

Exenatide improved the BP and blood lipid level of T2DM patients for 7 consecutive years in a DURATION open-extension study [37]

Another study showed that GLP-1R knockout mice have impaired LTP when compared to control animals ( These previous studies together suggest that GLP-1 may improve memory and cognitive function in patients with depression by enhancing synaptic function and neuronal signal transmission in the brain

We further demonstrate their pivotal role in anti-infective immunity, underscoring their ability to synthesize and secrete immune molecules, effectively capture and eliminate pathogens, and precisely regulate inflammatory responses and immune homeostasis