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Methods Transbilayer solute diffusion simulations Unbiased atomic detail MD simulations were performed using GROningen MAchine for Chemical Simulations (GROMACS) (www.gromacs.org) 17 , in combination with the Chemistry at HARvard Macromolecular Mechanics (CHARMM) 18 general force field (CGenFF) 19 for molecular solutes and the transferable intermolecular potential with 3 points (TIP3P) water model as solvent 20 , Lipids parameters were taken from the CHARMM36 all-atom force field 21

Each person was given 3 mg of vitamin B12 in one form, waited 14 days for a wash out period, and then took the other form (N=18)

We identify our work and perspective with Richards emphasis that for climate change and innovative projects to blossom, there needs to be stakeholder alignment between the community, policymakers, and designers