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Importantly, the QMP-engineered GLP-1 albumin fusion did not only display improved PK properties, but also demonstrated a prolonged therapeutic effect in healthy human FcRn Tg32 mice challenged with a high dose of glucose

Normal distribution of data was assessed with ShapiroWilk test and statistical analyses were determined with either unpaired t-test, two-way, or three-way analysis of variance (ANOVA) and post-hoc pairwise comparisons corrected according to Dunnetts or Sidaks method

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Combination therapy expansion for metabolic comorbidities rounds out the top-tier trends