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Consider adjuncts like metformin, which can enhance insulin resistance and increase endogenous GLP-1 secretion

While it was initially reported that mice deficient in Insl5 were mildly glucose-intolerant (170), this appears to be age (170) and strain-dependent (164, 168)

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How Winnett Specialist Group Can Help At the Winnett Specialist Group we perform many bariatric surgeries including the Orbera Intragastric Balloon, the Adjustable Gastric Band, Sleeve Surgery and Roux-en-Y Gastric Bypass, says Mr Winnett