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Reversal of diet-induced obesity in mice The defining study, Neelakantan and colleagues in Biochemical Pharmacology (2018), reported that a potent methylquinolinium NNMT inhibitor reduced body weight, white-fat mass, adipocyte size and plasma cholesterol in diet-induced obese mice, without changing food intake or causing overt adverse findings [1]
Healthy mitochondrial function is associated with: Energy production Cellular repair Muscle performance Brain function Longevity Research suggests Epitalon may contribute to improved mitochondrial efficiency
A person with lupus might be more likely to benefit from discussing a GLP-1 medicine with their clinician if they have: Type 2 diabetes Obesity or overweight with weight-related health problems High blood pressure High cholesterol Fatty liver disease High cardiovascular risk Kidney risk factors Difficulty losing weight despite serious lifestyle efforts These medicines may be especially worth discussing when weight, diabetes, or cardiovascular risk is making lupus care more difficult
doi: 10.1002/cam4.70725 79 van TilburgCMWittRHeissMPajtlerKWPlassCPoschkeIet al
