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This review systematically introduces the antioxidant mechanism of NAC, analyzes the advancements in NAC-related research involving mesenchymal stem cells, precursor cells, innate immune cells and animal models, discusses its function using the classic oral microenvironment as an example, and places particular emphasis on the innovative applications of NAC-modified tissue engineering biomaterials

It is also described in mechanistic contexts involving nitric oxiderelated pathways, growth factor expression, and cellular processes tied to migration and adhesionconcepts often studied when researchers are investigating how tissues respond and reorganize after experimental injury or stress

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