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Inhalation exposure Groups of 10 - 20 Wistar rats per sex, 8 guinea-pigs per sex, 1 - 2 rabbits per sex, and 1 - 2 female rhesus monkeys were each exposed to concentrations of ethylene oxide at levels of 0, 90, 200, 370, 640, or 1510 mg/m 3 , for 7 h per day, and 5 days per week
Bachier C, Giles RE, Ellerson D, Hanania EG, Garcia-Sanchez F, Haley T, Andreeff M , Cabanillas F, Champlin R, Berenson R, Heimfeld S, Deisseroth AB
Ethacrynic acid and quinine, which are both GST inhibitors, have been reported to reverse the resistance to melphalan and doxorubicin of cancer cell lines with increased GST expression [25]