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Melanotan 1 Highly selective for the MC1R receptor Produces more gradual and stable pigmentation effects among research models Has a narrower range of systemic effects when administered within research settings Melanotan 2 Broader receptor affinity as compared to Melanotan 1 Demonstrates faster pigmentation responses in animal models Broader receptor affinity could lead to a wider spectrum of possible adverse effects From a research viewpoint, Melanotan 1 is better characterized for photoprotection and pigmentation research studies

Although there is not a cure for the disease, the most used and cheaper treatment for PD continues to be Levodopa [1,8]

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