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Large-scale real-world data and clinical trials indicate that GLP-1RAs reduce alcohol intake even among those without the explicit goal of quitting alcohol consumption. More Evidence That GLP-1 Drugs Can Curb Alcohol Cravings In another study ( JAMA Psychiatry, Feb

This calcium overload activates Tau kinases, such as GSK-3 and CDK5, thereby promoting Tau phosphorylation and exacerbating the pathological process of Alzheimers disease [117]