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About 8 percent of adults considered GLP-1s extremely risky in February 2026 compared to 15 percent in May 2024

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Dehydration GLP-1 patients are already at risk of dehydration from reduced fluid intake and occasional vomiting/diarrhoea

The earliest we might see FDA approval is late 2027, and a subsequent insurance formulary adoption would likely push its widespread availability back to 2028 or 2029