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Increasing soluble fibre intake gradually (through foods such as oats, bananas, and cooked vegetables) can help regulate bowel movements, though patients should be cautious not to increase fibre too rapidly, as this may worsen bloating
The study also recorded lifestyle factors, such as current smoking status, based on patient self-reports documented in the medical histories within the EMRs dataset
Collectively, the integrated therapeutic strategies targeting ferroptosis, pyroptosis, and necroptosisincluding RCD inducers combined with ICIs, nanotechnology-driven precision delivery systems, and multi-targeted approaches to overcome metabolic plasticity and off-target toxicitiesprovide a comprehensive framework to enhance melanoma immunotherapy efficacy ( Figure 4 )
Outpatient treatment of propionic acidemia-associated hyperammonemia with N-carbamoyl-L-glutamate in an infant
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