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This interconnection explains why anxiety reports on GLP-1 therapy vary significantly among individuals with similar doses and treatment duration

10.1002/jmri.26046 84

When oxidative stress (e.g., H 2 O 2 treatment) leads to an increase in mitochondrial membrane permeability, mt-dsRNA leaks into the cytoplasm through voltage-dependent anion channels (VDAC) to form a pool of stress granule-associated free dsRNA [166]

However, these drugs are not devoid of side effects, necessitating careful consideration and medical guidance for their usage