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GLP-1 side effects include gastrointestinal complications, such as nausea, vomiting, diarrhea, constipation, and diverticulitis

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Postprandial hyperinsulinaemia Less suppression of insulin secretion in the presence of hypoglycaemia and greater sensitivity of cells to increased blood glucose levels have been described after GBP7, mediated both by intestinal hormonal factors (increase in GLP-1 secretion)8,9 and by non-hormonal factors68 (postprandial elevation of unconjugated bile acids)7, which will be accompanied by an earlier and more intense peak of postprandial insulinaemia.7,8 One of the first hypotheses proposed was the increase in the mass of pancreatic cells with nesidioblastosis, as a result of the exaggerated secretion of GLP-110