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This hypothesis derives from the fact that drugs, including phenylcyclohexylpiperidine (PCP), cause schizophrenia-like psychotic symptoms in humans by blocking the function of the NMDA receptor, and that such psychotic symptoms are difficult to diagnostically distinguish from schizophrenia ( Previous studies on schizophrenia has predominantly concentrated on dopaminergic and glutamatergic neurotransmitters

This conversion requires the enzyme glutamatecysteine ligase (GCL, glutamate-cysteine synthase)

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Asymmetric (ADMA) and symmetric (SDMA) dimethylarginines in chronic kidney disease: a clinical approach