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While in animals it mediates neurotransmission, neuromodulation, and synaptic plasticity, in plants it regulates seed germination, root development, stomatal closure, and floral transition (Forrester et al

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*Correspondence: Weina Li, [email protected] Meng Li, [email protected] These authors have contributed equally to this work This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Using white opaque luminescence plate on ice, 25 l of the diluted worm acid supernatant was added each well in triplicates