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Many patients experience an average weight loss of 10% to 18% of their starting body weight, and some lose 15% to 21% of their body weight over 68 weeks, depending in part on starting weight

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However, losing weight quickly has many health risks, including: 6 Vitamin and mineral deficiencies Muscle loss Malnourishment Decreased metabolism Additionally, using Topamax for weight loss can increase the risk of disordered eating behaviors as well as the risk of developing full-blown eating disorders like anorexia nervosa (AN) and bulimia nervosa (BN)

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