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The figure 25.3 % surpasses: Tirzepatide SURMOUNT-1: 22.5 % Semaglutide STEP-1: 14.9 % Retatrutide Phase 2: 24.2 % (comparable, but Phase 3 results for Retatrutide are still lacking) It raises the question whether CagriSema will be the first molecule with an effect truly comparable to bariatric surgery (typically 2530 % reduction)

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[DOI] [PubMed] [PMC] Stocks B, Ashcroft SP, Joanisse S, Dansereau LC, Koay YC, Elhassan YS, et al