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Description

Indeed, high exposure may sometimes attenuate efficacy via the hook effect

Not for those over 65 or with heart disease

This means the compound may keep testosterone from changing into dihydrotestosterone (DHT)

Disproportionality analysis A sequential approach was adopted to systematically address major confounders: (1) An exploratory disproportionality approach comparing GLP-1RAs with all other drugs reported in the FAERS database, using venlafaxine as the positive control and empagliflozin/orlistat as the negative control