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Incretin mimetics are particularly suitable for: Patients where weight loss would provide additional health benefits Individuals at high cardiovascular risk who may benefit from the cardioprotective effects of certain agents (liraglutide, semaglutide, dulaglutide) Patients wishing to avoid or delay insulin therapy Those requiring substantial HbA1c reductions to reach target levels NICE NG28 specifies continuation criteria for GLP-1 receptor agonists in triple therapy: continue only if there is a beneficial metabolic response, defined as a reduction of at least 11 mmol/mol (1.0%) in HbA1c and weight loss of at least 3% of initial body weight at six months

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Patients with diabetes should also monitor blood glucose, as dehydration and illness can affect glycemic control

Comparison of the absorption and excretion of three commercially available sources of vitamin C