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CKD affects the bioavailability and pharmacokinetics of direct oral anticoagulants since they are all, at least partially, excreted by the kidneys (the renal clearance of dabigatran is around 80%, of edoxaban 50%, of rivaroxaban 33%, and of apixaban 27%) and may require dose adjustments in patients with reduced eGFR

The test maps 14 distinct metabolic pathways across 49 peptides, delivering over 150 genetic insights relevant to weight loss and appetite regulation

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Nrf2 plays a critical role in maintaining cellular function and viability, particularly during stress