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4.3 GSH metabolism: a central hub in mid-late SAE The hippocampus, with its high metabolic demands and low antioxidant capacity, is uniquely vulnerable to septic injury (Yuan et al., 2020)

2017;12(5):e0177953 Sol J, Obis , Mota-Martorell N, Pradas I, Galo-Licona JD, Martin-Gar M, et al

KPV: This peptide acts as a potent "Fire Suppressor." Its main role is to calm inflammation, making it particularly effective for soothing irritation in the gut and skin

The driving force of the reaction is the formation of the triazole ring, which displays great stability due to the aromatic properties of the ring (G = 61 kcal mol 1 ) [106]