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However, in the case where hospitals need additional time to pull or prepare the data before posting the MRF, hospitals may use data from up to 15 months prior to the date the file is posted to help ensure they have adequate data to encode the allowed amounts

=It is speculated that semaglutide (or associated rapid metabolic/vascular changes) may affect optic nerve head perfusion (blood flow) or affect vascular risk in susceptible individuals

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The answer comes down to what "sterile" and "0.9%" actually require at a pharmaceutical level and why falling short of either standard creates contamination risk that is invisible until something goes wrong