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Description

46 APAP can freely cross the selective maternal-fetal barrier of the placenta, after which it can then be metabolized by fetal hepatocytes, causing fetal hepatic necrosis if appropriate therapy with NAC is not administered in a timely manner

It includes the successive oxidation and reduction of AsA and GSH with a cyclic transfer of reducing equivalents so that the plant-specific ascorbate peroxidase (APx) is able to reduce H 2 O 2 to H 2 O