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Case 1 Mr Sharma is a 65-year-old man with type 2 diabetes mellitus and hypertension

The recommended dietary allowance (RDA) of 0.8 grams per kilogram body weight is sufficient to prevent deficiency but may be inadequate for optimal muscle development

Mechanistically, calcitriol upregulates key lipid-synthesizing enzymesincluding fatty acid synthase (FAS), 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA reductase), and serine palmitoyltransferase (SPT)and promotes lamellar body maturation and secretion, thereby enhancing stratum corneum structural cohesion [234,235,236]

The DA's office runs a screening intake every case gets reviewed for charge accuracy and evidence sufficiency before the first court date