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Although GLP-1RAs are often thought to be linked to a relatively lower risk of hypoglycemia (13), the combination of GLP-1RAs and other anti-diabetic medications (e.g., sulphonylureas) have shown an elevated risk of hypoglycemia compared to placebo (14)

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In patients with type 2 diabetes - characterized by insulin resistance and insufficient insulin production - regulation is impaired, leading to chronic hyperglycemia

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