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2.2 Clinical Data Clinical data were derived from the STEP-8 clinical trial, a randomized, open-label, 68-week, phase III trial conducted in the USA that compared the efficacy and safety of once-weekly semaglutide 2.4 mg and liraglutide 3 mg (both with diet and physical activity) in adults with BMI 30 or 27 with one or more weight-related comorbidities, without diabetes [22]

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Thus, larger emission of MMB in Iriomote cats than in Tsushima leopard cats would indicate that the pathway is upregulated in Iriomote cats as compared to Tsushima leopard cats

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