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The NHS lists the common symptoms as: Persistent tiredness, breathlessness and a lack of energy Pins and needles, numbness or tingling in the hands and feet A sore, red tongue and mouth ulcers Problems with memory, concentration and mood Pale or slightly yellow-tinged skin If several of these sound familiar and you are on long-term metformin, that is a good reason to ask your GP for a B12 blood test rather than to book an injection straight away

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13,14 On this foundation, substantial research into the genesis of autism has been conducted, including molecular genetics, neuroimmunity, functional imaging, neuroanatomy, and neurochemistry research