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Beyond obesity, retatrutide is being investigated for type 2 diabetes and metabolic dysfunction-associated steatohepatitis (MASH), conditions where the combination of weight loss, improved glycemic control, and enhanced hepatic fat oxidation could provide comprehensive therapeutic benefits

It is also too early to know what impact quitting has on long-term health (Youmshajekian) Acknowledgements This piece was originally published in April 2025 by Lara Marks with the generous help of Svetlana Mojsov, Jens Holst and Richard Ng who read early drafts

Diabetes 62 , 16971708 (2013)

Tichansky DS, Glatt AR, Madan AK, Harper J, Tokita K, Boughter JD