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Honest TruthOne of the most common misconceptions patients have before starting treatment is

Naseem MU, Carcamo-Noriega E, Beltrn-Vidal J, Borrego J, Szanto TG, Zamudio FZ et al (2022) Cm28, a Scorpion toxin having a unique primary structure, inhibits K V 1.2 and K V 1.3 with high affinity

Disrupting this pathwayeither by severing kidney sensory nerves, selectively deleting the angiotensin II type 1a receptor (AT1a) in the subfornical organ (SFO), or using optogenetics to silence the kidney-SFO or SFO-paraventricular nucleus (PVN) connectionsreduces sympathetic output, which in turn diminishes structural damage and functional impairment in the kidneys and heart in these models of CKD and heart failure (Cao et al., 2023)

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