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It manifests with a noticeable loss of fat in areas like the arms, legs, or face, and accumulation in other areas like the abdomen and around internal organs

NNMT activity is known to increase as aging progresses or in response to certain lifestyle factors, often resulting in a decline in metabolic efficiency and a buildup of stubborn fat

Excessive alcohol consumption also reduces glutathione production and increases the demand for this master antioxidant in detoxification processes

[DOI] [PMC free article] [PubMed] [Google Scholar] 266.Rasic D., Zenko Sever A., Rasic F., Strbe S., Rasic Z., Djuzel A., Duplancic B., Boban Blagaic A., Skrtic A., Seiwerth S., et al