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Qsymia follows a structured dose-escalation plan: Initial dose: 3.75 mg/23 mg (phentermine/topiramate) for 14 days Standard dose: 7.5 mg/46 mg (phentermine/topiramate) for 12 weeks After 12 weeks of treatment, your healthcare provider evaluates your response: If you lost at least 3% of your baseline body weight, treatment may continue at your current dose

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