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Daily use provides better results compared to irregular intake

The study results also showed that dysesthesia and urinary tract infections were reported in around one in ten patients on the highest doses of retatrutide but they were generally mild-to-moderate symptoms and the majority were resolved during treatment, while most participants continued taking retatrutide

The study identified a higher number of patients with retained gastric contents in those undergoing EGD alone compared to no gastric contents in those undergoing combined EGD-colonoscopy ( It is unclear if the risks are lower with the combination of holding the medication and also having a bowel prep, if one of these approaches may be sufficient to reduce risks, or if even a clear liquid diet without a bowel prep could also be just as effective

Some of the common side effects associated with GLP-1 treatments include: Gastrointestinal Issues: GLP-1 medications can sometimes cause nausea, vomiting, diarrhea, or constipation, especially during the initial stages of treatment