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GLP-1RAs prevent post-MI remodeling by having an impact on the extracellular matrix changes rather than dependency on its glycemic control [76]

First, a systematic search was conducted in PubMed, Web of Science, and Embase from inception to March 2026 using combinations of tinnitus AND (neurodegenerative diseases OR Alzheimer disease OR Parkinson disease) AND (treatment OR therapy OR intervention), supplemented with mechanism-specific terms paired with tinnitus (e.g., neuroinflammation, oxidative stress, BDNF, NMDA receptor, epigenetic)

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Sanofi withdrew its US marketing application for the drug in 2013 after an FDA request for more safety data and armed with the ELIXA results the company has indicated it will press ahead with a fresh filing in the US